Conference Proceedings
Risk factors for metachronous colorectal cancer following a primary colorectal cancer: A prospective cohort study
H Jayasekara, JC Reece, DD Buchanan, C Rosty, S Ghazaleh Dashti, DA Ouakrim, IM Winship, FA MacRae, A Boussioutas, GG Giles, DJ Ahnen, J Lowery, G Casey, RW Haile, S Gallinger, L Le Marchand, PA Newcomb, NM Lindor, JL Hopper, S Parry Show all
International Journal of Cancer | Published : 2016
DOI: 10.1002/ijc.30153
Abstract
Individuals diagnosed with colorectal cancer (CRC) are at risk of developing a metachronous CRC. We examined the associations between personal, tumour-related and lifestyle risk factors, and risk of metachronous CRC. A total of 7,863 participants with incident colon or rectal cancer who were recruited in the USA, Canada and Australia to the Colon Cancer Family Registry during 1997-2012, except those identified as high-risk, for example, Lynch syndrome, were followed up approximately every 5 years. We estimated the risk of metachronous CRC, defined as the first new primary CRC following an interval of at least one year after the initial CRC diagnosis. Observation time started at the age at di..
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Awarded by National Cancer Institute